HIV Post Exposure Prophylaxis (HIV PEP) for HIV Prevention
been exposed to HIV within the last 72 hours? HIV can be prevented with HIV PEP treatment.
WHAT IS HIV PEP / HIV PREVENTION / HIV POST EXPOSURE PROPHYLAXIS?
HIV POST-EXPOSURE PROPHYLAXIS (PEP) is short-term antiretroviral treatment and medication to reduce the chance of HIV infection after potential exposure, through sexual intercourse, sexual assault, injection-drug use and other potential exposures.
When started within 72 hours from exposure, HIV PEP treatment has been shown to decrease the odds of HIV transmission with an exposure by 81%.
HIV Post Exposure Prophylaxis (PEP) or HIV Prevention is the use of antiretroviral (ARV) medications to prevent or to stop the human immunodeficiency virus (HIV) from entering and infecting the body after exposure.
Antiretroviral (ARV) medications or antiretroviral therapy (ART) has become the standard of care for healthcare workers who have had accidental occupational exposure to HIV for e.g. needlestick injuries or contact of mucous membrane or exposed skin to potentially infectious material such as blood or bodily fluids.
Post Exposure Prophylaxis (PEP) has also been offered to people who have had non-occupational exposure to HIV for e.g. sexual exposure or injection drug use.
A non-occupational high-risk exposure refers to:
any unprotected anal or
vaginal intercourse, receptive oral intercourse with ejaculation with a partner
known to be HIV-infected, or in HIV risk group (commercial sex workers, IV drug
users, men who have sex with men/ bisexual men) or
sharing of or exposure to contaminated needles
sexual assault (rape)
HIV PEP treatment has been shown to decrease the odds of HIV transmission with an exposure by 81%.
When should HIV PEP / HIV Post Exposure Prophylaxis (PEP) be started?
HIV PEP should be started as soon as possible after exposure
up to 72 hours. The ideal time period to start PEP is within 24 hours from
exposure, although it has been shown to be effective up to 72 hours
post-exposure. The earlier HIV PEP is started, the more effective it is in
preventing HIV transmission and infection.
Exposure and Estimated Risks
Needle stick injury: 1/300
Receptive anal intercourse: 1/100
Receptive vaginal intercourse: 1/1000
Insertive vaginal intercourse: 1/2000
Insertive anal intercourse: 1/2500
Receptive fellatio with ejaculation: 1/2500
Sharing needles: 1/150
Generally, exposures to
saliva, urine, tears and sweat are not thought to be infectious, and the risk
of HIV transmission from splashes of contaminated fluids to mucosal surface or
non-intact skin has not been accurately quantified, although it is likely to
Are other forms of STD/STI testing required?
If you have had a high risk exposure, we would also recommend testing for other common STDs or STIs such as syphilis, gonorrhea and chlamydia. Our STD/HIV clinic provides a full range of STD and STI testing services which can be done at the same time as the HIV testing. Please see here for a full list of STD testing and screening profiles. HIV and STD tests can be customized to suit your risk profile. The timing of the testing should be discussed with our doctor but generally we recommend testing at 2 weeks, 1 month and 3 months.
HIV PEP Treatment
This is a typical HIV PEP treatment process at our clinic:
Consultation - To advise if you are a right
candidate for HIV PEP treatment
Rapid HIV test - To ascertain that you are
currently HIV negative
Baseline blood tests - To make sure that your
vital organs are functioning normally. If you are generally healthy, taking HIV PEP treatment would not cause any problems to your health.
START PEP TREATMENT - Daily medication for a
month (A combination of 2 – 3 antiretroviral drugs)
Follow-up blood and HIV tests - after 1 month
and 3 months post-exposure
For a private consultation with our doctors on whether you
are a suitable candidate for PEP treatment, please call us for an appointment. The full course HIV PEP treatment costs are between $2000 - $2400.
For HIV PEP treatment, visit Nuffield Medical Siglap - medical clinic at Siglap, Singapore. All consultations and testing are strictly private and confidential. Please Call 66363083 or SMS 98375754 or Email firstname.lastname@example.org.
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